RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
Malat1
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; Masson's trichrome staining
Target
MIR-145
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Long noncoding RNA MALAT1 mediates cardiac fibrosis in experimental postinfarct myocardium mice model
Year
2019
Function
Lncrna malat1 promotes cardiac fibrosis and deteriorates cardiac function post-myocardial infarction (MI) by regulating TGF-beta activity via miR-145.